affron® References

  1. Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: a randomized, double-blind, placebo-controlled trial. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 16(6), 937–947.Lopresti, A. L., Smith, S. J., Metse, A. P., & Drummond, P. D. (2020).
  2. affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomised, placebo-controlled clinical trial. Complement Ther Med. 2017 Aug;33:58-64 Kell G, et al. 
  3. Epidemiology of Premenstrual Syndrome (PMS)-A Systematic Review and Meta-Analysis Study. Journal of clinical and diagnostic research : JCDR, 8(2), 106–109. A, D. M., K, S., A, D., & Sattar, K. (2014).
  4. Psychological and neuroendocrinological effects of odor of saffron (Crocus sativus). Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(8-9), 726–730. Fukui, H., Toyoshima, K., & Komaki, R. (2011).
  5. Saffron and crocin improved appetite, dietary intakes and body composition in patients with coronary artery disease. Journal of cardiovascular and thoracic research, 9(4), 200–208. Abedimanesh, N., Bathaie, S. Z., Abedimanesh, S., Motlagh, B., Separham, A., & Ostadrahimi, A. (2017).
  6. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo- controlled study. J Affect Disord. 2017 Jan 1;207:188-196. Lopresti AL, et al.
  7. affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study. J Affect Disord. 2018 May;232:349-357. Lopresti AL, et al.
  8. Sleep enhancement by saffron extract in randomised control trial, Japanese Pharmacology and Therapeutics. Japanese Pharmacology and Therapeutics. 2018 (8); 46:1407-1415. Nishide, A, et al.
  9. New clinical evidence of affron® efficacy as an adjunct treatment for unremitted depression. J Psychopharmacol. 2019. Nov;33(11):1415-1427. Lopresti AL, et al.
  10. Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation. Phytotherapy research : PTR, 14(3), 149–152. Abe, K., & Saito, H. (2000).
  11. Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review. Critical reviews in food science and nutrition, 1–24. Advance online publication. Abu-Izneid, T., Rauf, A., Khalil, A. A., Olatunde, A., Khalid, A., Alhumaydhi, F. A., Aljohani, A., Sahab Uddin, M., Heydari, M., Khayrullin, M., Shariati, M. A., Aremu, A. O., Alafnan, A., & Rengasamy, K. (2020). 
  12. Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms. Avicenna journal of phytomedicine, 5(5), 365–375.Mokhtari-Zaer, A., Khazdair, M. R., & Boskabady, M. H. (2015). 
  13. Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review. Iranian journal of basic medical sciences, 19(5), 455–469. Khorasany, A. R., & Hosseinzadeh, H. (2016).
  14. Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review. Iranian journal of basic medical sciences, 22(4), 334–344. Zeinali, M., Zirak, M. R., Rezaee, S. A., Karimi, G., & Hosseinzadeh, H. (2019). 
  15. Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview. Phytotherapy research : PTR, 32(12), 2364–2375. Leone, S., Recinella, L., Chiavaroli, A., Orlando, G., Ferrante, C., Leporini, L., Brunetti, L., & Menghini, L. (2018).

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