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affron® is an Award Winning herb

USA Award-winner Ingredient for Cognitive Health 2020

“An extraordinary Saffron extract of the highest quality, endorsed by 6 human clinical studies, patented, and with well-defined mechanisms of action.”

NUTRAINGREDIENTS.COM

What is Saffron?

Saffron is a spice derived from the flower of Crocus sativus, it has been used for more than 3,500 years and extends across many cultures, continents, and civilisations.The cultivation of Saffron requires intensive labour and time making it a highly priced spice. The collected stigmas are the medicinally active component of the plant, but it takes about 36,000 flowers to yield just 1 pound of the stigmas, which also increases the value of this plant as a medicinal herb. Saffron has been used in traditional folk medicines and Ayurvedic health systems as a herbal sedative, digestive aid, anti-inflammatory, expectorant and adaptogenic agent for centuries. Saffron is known as a ‘yogavahi’ herb in Ayurveda as it acts as a catalyst for other herbs it is taken with.

 

What is affron®?

affron® is a premium Saffron ingredient standardized to 3.5% Lepticrosalides™, which is responsible for the beneficial properties and organoleptic properties of affron®. It is backed by six human clinical studies that have shown to improve quality sleep. affron® uses a patented low temperature proprietary extraction process that creates superior Saffron quality with long-lasting active stability.  This process results in the highest quality of Saffron while producing less industrial processing, energy and zero chemicals. affron® is internationally patented both with its formulation and effects on health with the lowest daily dose of only 28 mg. It is the world's first clinical studied version of Saffron proven to help sleep, mood, cognition and vitality. affron® is creating a buzz amongst academics and scientists as the first Saffron extract on the market to be supported with peer-reviewed clinical evidence to demonstrate positive benefits across sleep quality. 

affron Saffron extract is used in our sleep supplement Sleep, to create the perfect restful state using only natural herbal supplements.

Issues with regular Saffron?

The Saffron market is full with products containing raw or dried Saffron, which will reduce the efficacy of Saffron, as they don’t hold the same active constituents as in a standardized Saffron extract such as affron®. There are also no other Saffron products on the market today that are backed by preclinical or clinical studies to prove its efficacy. 

 

Why do we use affron® in our Sleep Complex?

affron® is the most widely published Saffron extract in the world. Proven to help maintain a positive mood and get restorative sleep, every day. affron® contains Lepticrosalides® > 3.5% (crocins >3.5%, safranal 0.03%) by HPLC-DAD. Lepticrosalides® is a complex of bioactive compounds responsible for the beneficial and organoleptic properties of affron®. affron® genuine quality relies on local trusted sourcing, the selection of the Spanish species Crocus sativus L. and the exclusive and proprietary extraction process that uniquely concentrates and preserves the actives with low energy use.

References

  1. Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: a randomized, double-blind, placebo-controlled trial. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 16(6), 937–947.Lopresti, A. L., Smith, S. J., Metse, A. P., & Drummond, P. D. (2020).
  2. affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomised, placebo-controlled clinical trial. Complement Ther Med. 2017 Aug;33:58-64 Kell G, et al. 
  3. Epidemiology of Premenstrual Syndrome (PMS)-A Systematic Review and Meta-Analysis Study. Journal of clinical and diagnostic research : JCDR, 8(2), 106–109. A, D. M., K, S., A, D., & Sattar, K. (2014).
  4. Psychological and neuroendocrinological effects of odor of saffron (Crocus sativus). Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(8-9), 726–730. Fukui, H., Toyoshima, K., & Komaki, R. (2011).
  5. Saffron and crocin improved appetite, dietary intakes and body composition in patients with coronary artery disease. Journal of cardiovascular and thoracic research, 9(4), 200–208. Abedimanesh, N., Bathaie, S. Z., Abedimanesh, S., Motlagh, B., Separham, A., & Ostadrahimi, A. (2017).
  6. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo- controlled study. J Affect Disord. 2017 Jan 1;207:188-196. Lopresti AL, et al.
  7. affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study. J Affect Disord. 2018 May;232:349-357. Lopresti AL, et al.
  8. Sleep enhancement by saffron extract in randomised control trial, Japanese Pharmacology and Therapeutics. Japanese Pharmacology and Therapeutics. 2018 (8); 46:1407-1415. Nishide, A, et al.
  9. New clinical evidence of affron® efficacy as an adjunct treatment for unremitted depression. J Psychopharmacol. 2019. Nov;33(11):1415-1427. Lopresti AL, et al.
  10. Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation. Phytotherapy research : PTR, 14(3), 149–152. Abe, K., & Saito, H. (2000).
  11. Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review. Critical reviews in food science and nutrition, 1–24. Advance online publication. Abu-Izneid, T., Rauf, A., Khalil, A. A., Olatunde, A., Khalid, A., Alhumaydhi, F. A., Aljohani, A., Sahab Uddin, M., Heydari, M., Khayrullin, M., Shariati, M. A., Aremu, A. O., Alafnan, A., & Rengasamy, K. (2020). 
  12. Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms. Avicenna journal of phytomedicine, 5(5), 365–375.Mokhtari-Zaer, A., Khazdair, M. R., & Boskabady, M. H. (2015). 
  13. Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review. Iranian journal of basic medical sciences, 19(5), 455–469. Khorasany, A. R., & Hosseinzadeh, H. (2016).
  14. Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review. Iranian journal of basic medical sciences, 22(4), 334–344. Zeinali, M., Zirak, M. R., Rezaee, S. A., Karimi, G., & Hosseinzadeh, H. (2019). 
  15. Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview. Phytotherapy research : PTR, 32(12), 2364–2375. Leone, S., Recinella, L., Chiavaroli, A., Orlando, G., Ferrante, C., Leporini, L., Brunetti, L., & Menghini, L. (2018).

The world is full of great products and formulas,
why should you buy from us?

The world is full of great products and formulas, why should you buy from us?

Our People

We are a small passionate tribe of like minded warriors who want to bring Earths Secret and the power of Nature to the world. Success for us is the difference we can make to peoples lives.

Peer Patented Ingredients

Created by Nature, proven by science. Our three Pillar ingredients are the most potent and bioavailable form of that ingredient possible. We don’t just make claims, we back them up with science: KSM-66®, Hydrocurc® and affron®.

Our complexes

We have explored the Earth for the most bioavailable, sustainable and effective ingredients. Individually these ingredients have been used for hundreds of years. Our unique Complexes empowers users to benefit form blending these powerful ingredients together and taking users health and wellness to the next level. The focus we put on the ingredients blend produces multiple times the absorption rate when compared to generic supplements.

Quality of Experience

Our products are of the highest standard available anywhere. Our service, delivery, packaging and sustainability are of the highest quality we truly can imagine. We will always strive to improve and we know this is as much a journey for us as it is for you.